The former 'O.C' actress said while she's open to performing kissing scenes, she prefers them to be between her and another girl, because it is less "tense" than kissing a man.
She said: "It's so much easier to kiss a girl. You're so much more relaxed filming than you are doing a guy and girl scene. You can relax and have a laugh about it, whereas if it's a man you have to kiss, the whole thing's a bit tense."
She added she finds it strange she keeps getting picked for roles that include lesbian scenes.
Mischa added: "I don't know why that keeps happening to me, but my scripts have a lot of girl-on-girl kissing. But if it's part of my character, that doesn't really annoy me.
"I did a film about Tatu, the Russian girl band, and that was interesting. This whole corrupt Russian music industry formed this fake lesbian band. It's an odd story but a fascinating one."
The British-born star also said while she's happy kissing on camera, she'd never pose fully nude in a magazine.
She said: "I took my top off for Cosmopolitan magazine, but I'd never do a fully nude shoot ? that's just not me. I was shot from the chest up and everyone speaks about it like I was naked. I really wasn't."